Modified on: February 27th, 2023
This report provides exploratory and preliminary correlation analyses between sex hormones and T2 final hippocampal subfield volume data from the Healthy Aging Study sample that have completed the spatial navigation study.
Cleaning data steps included (T2 subfields):
Filter participants that have useable T2 subfield data from scan and completed spatial navigation behavior
Select sex hormone measures from when spatial study was conducted
Values were already averaged together (left and right) and already corrected with TIV
For left and right subfields, they have already been corrected with TIV
Calculating Total Hippocampal Volume:
Sum up the averaged CA1, CA23, DG, SUB to get T2 total hippocampal volumes
Left and right volumes are by adding respective left and right subfields
Calculating Total MTL:
Sum up the averaged CA1, CA23, DG, SUB, ERC, PHC, PRC to get MTL volume
Left and right volumes are by adding respective left and right subfields
| Sex | n | Mean Age | SD Age |
|---|---|---|---|
| Female | 15 | 50.27 | 3.26 |
| Male | 11 | 49.18 | 2.93 |
Above table shows the table of sample size and mean and standard deviation of age by sex for overall group who have completed spatial behavior and have a useable T2hipp scan.
Shapiro-Wilk’s test reveal that LOOP degrees traveled at 3.0m for men and averaged angular error for overall and for men were not normally distributed. Behavior and volume correlations will be Spearman rank
All correlations are Pearson
All correlations were Pearson except for men (Spearman)
All correlations were Pearson except for men (Spearman)
All correlations were Pearson except for men (Spearman)
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations were Pearson
All correlations were Pearson
All correlations are Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson except for men (Spearman)
All correlations are Pearson except for men (Spearman)
All correlations are Pearson except for men (Spearman)
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
Al correlations are Pearson
All correlations are Pearson except for men (Pearson)
All correlations are Pearson except for men (Pearson)
All correlations are Pearson except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman
All correlations were Spearman
All correlations were Spearman
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson except for men (Spearman)
All correlations are Pearson except for men (Spearman)
All correlations are Pearson except for men (Spearman)
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Spearman except for men (Pearson)
All correlations were Pearson
All correlations are Pearson
All correlations are Pearson except for men (Spearman)
All correlations are Pearson except for men (Spearman)
All correlations are Pearson except for men (Spearman)
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations are Spearman except for men (Pearson)
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson except for men
All correlations were Pearson except for men
All correlations were Pearson except for men
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations are Spearman except for men
All correlations are Spearman except for men
All correlations are Spearman except for men
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall correlation was Pearson, rest were Spearman.
All correlations were spearman except for overall
All correlations were Spearman except for overall
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
Overall and male correlations were Pearson, female and repo groups were Spearman.
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson except for men
All correlations were Pearson except for men
All correlations were Pearson except for men
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Pearson
All correlations are Spearman except for men
All correlations are Spearman except for men
All correlations are Spearman except for men
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson except for men
All correlations were Pearson except for men
All correlations were Pearson except for men
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Pearson
All correlations were Spearman except for men
All correlations were Spearman except for men
All correlations were Spearman except for men
Sample included HAS participants who had a T2 hipp scan and completed spatial navigation behavior for LOOP.
LOOP greater degrees traveled (3.0m and averaged) was significantly negatively correlated with lower total hipp volume within overall (women and men together) for averaged, left, and right volumes.
For men, total hipp volume was negatively correlated with degrees traveled averaged for averaged, left, and right volumes. Averaged totla hipp volume was only negatively correlated with degrees traveled at 3.0m for the average volume.
For women, total hipp volume was negatively correlated with degrees traveled at 3.0m for averaged and left total hipp volumes. Left total hipp volume was negatively correlated with degrees traveled averaged for women.
LOOP position error was significantly negatively correlated with lower PHC volume within overall (women and men).
LOOP greater degrees traveled at 3.0m and averaged was significantly negatively correlated with lower volumes in CA1, CA23, DG, and SUB for overall. For men, negative correlations are observed for DG only at 3.0m, but seen in CA1, CA23, and DG for degrees traveled averaged. For women, negative correlations are observed for CA1, CA23, and SUB for 3.0m, and only for CA1 and CA23 for degrees traveled averaged.